Ion Chromatography Standards
Apexbio Technology LLC WZ811 55778-02-4 1g
WZ811 (CAS 55778-02-4) is a small molecule antagonist targeting the CXC chemokine receptor 4 (CXCR4) Structurally composed of two aromatic amine groups WZ811 inhibits the binding of TN14003 to CXCR4 with an EC50 of 0 3 nM and disrupts stromal cell-derived factor 1 (SDF-1)-mediated CXCR4 signaling In cAMP assays WZ811 significantly attenuates SDF-1-induced cAMP responses and impedes SDF-1-driven Matrigel invasion (EC50 5 2 nM) Given CXCR4 s involvement in infection inflammation and various diseases WZ811 serves as a valuable tool for interrogating CXCR4-related biological processes and disease models and has been reported to display modest anti-HIV activity in cell cultures
Apexbio Technology LLC Tebuconazole 107534-96-3 1g
Tebuconazole (CAS 107534-96-3) is a small-molecule inhibitor targeting CYP51 a key enzyme in fungal sterol biosynthesis It modulates CYP51 activity to regulate sterol production within fungal cells Tebuconazole exerts its biological activity primarily through inhibition of CYP51 In cell-based assays tebuconazole demonstrates inhibitory activity with an IC50 value of 0 9 M against CaCYP51 from Candida albicans and 1 3 M against truncated human 60HsCYP51 Additionally in HepG2 cells tebuconazole induces lipid accumulation and oxidative stress and in mammary epithelial MAC-T cells it reduces proliferation and induces endoplasmic reticulum stress-mediated apoptosis Based on these pharmacological properties tebuconazole holds research potential in studies of fungal sterol biosynthesis cellular stress response pathways and apoptosis mechanisms
Apexbio Technology LLC Casanthranol 8024-48-4 1g
Casanthranol is a natural mixture of anthranol glycosides derived from the bark of Rhamnus purshiana commonly known as cascara sagrada Casanthranol exerts its biological activity primarily through intestinal bacterial hydrolysis releasing anthraquinone aglycones that interact with colonic mucosa to enhance bowel motility and stimulate fluid accumulation in the intestinal lumen Based on these pharmacological properties casanthranol holds research potential in studies of intestinal motility investigation of laxative mechanisms microbiota-mediated glycoside metabolism and as a chemical probe for elucidating gastrointestinal physiology and anthraquinone glycoside bioactivity
Apexbio Technology LLC PNPG 2492-87-7 1g
PNPG (2492-87-7) is a chromogenic substrate utilized for quantitative determination of -D-glucosidase activity It is designed to enable measurement of -D-glucosidase-mediated hydrolysis thereby facilitating assessment of glucosidase function and glucoside breakdown pathways PNPG exerts its biological activity primarily through enzymatic hydrolysis by -D-glucosidase producing para-nitrophenol which exhibits a yellow color detectable at 405 nm via spectrophotometry Based on these properties PNPG holds research potential in biochemical assays for measuring -D-glucosidase activity enzyme kinetics and studies of glucose metabolism in biomedical and pharmacological research
Waters Corp Ammonia N Calibration Standard, 1000 mg/L, 125 mL, Aqueous
This Ammonia as N Ion Calibration Standard contains 1000 mg/L of Ammonia as N in H2O. It can be used for primary calibration or to prepare second source calibration check standards, and is traceable to NIST Standard Reference Materials where available. This CRM is covered by ISO 17034 accreditation and is guaranteed stable for one year.
- Certified Reference Material (CRM).
- Accredited to ISO 17034.
- Suitable for EPA 350.1, EPA 350.2, EPA 350.3, SM 4500-NH3 B, SM 4500-NH3 C, SM 4500-NH3 D, SM 4500-NH3 E, SM 4500-NH3 F, SM 4500-NH3 G methods.
- Storage at 20°C to 25°C (ambient).
- Shelf life of 24 months from date of manufacture.
- Minimum shelf life of 12 months on ship date.
- One component per package.
- Provided in a 125 mL poly bottle.
- Liquid formulation.
- Ideal for environmental applications.
Apexbio Technology LLC Rebamipide 90098-04-7 1g
Rebamipide (CAS 90098-04-7) is a small molecule administered orally and recognized for its gastroprotective properties Its primary mechanism involves upregulation of cyclooxygenase-2 (COX-2) expression which leads to increased endogenous prostaglandin synthesis particularly prostaglandin E2 (PGE2) thereby enhancing gastric mucosal defense Studies also indicate that rebamipide can inhibit the proliferation of gastric cancer cells This compound is utilized in research investigating the mechanisms underlying gastric mucosal injury peptic ulcer disease gastritis and gastric cancer
Waters Corp Ion Calibration Standard, Nitrite as N, 1000 mg/L, 125 mL
This ion calibration standard is designed for primary calibration or to prepare second source calibration check standards.
- Nitrite as N
- 1000 mg/L concentration
- 125 mL volume
- H2O matrix
- Traceable to NIST Standard Reference Materials
- Guaranteed stable for one year
AccuStandard, Inc SNION STD-NITRATE AS NITRO 500
Anion Standard - Nitrate as Nitrogen. 100 mL. 100 ?g/mL in Water.
SPEX CERTIPREP LLC 3P Nitrate from Sodium Nitrate at 1,000 ug/mL in H2O, 100 mL
(HPS by Zeptometrix) Nitrate Anion IC Single-Component Standard from Sodium Nitrate at 1,000 ug/mL in H2O. Can be used as stock solution for nitrate as nitrate, EPA Method 9056. If you need to report Nitrogen using a nitrate source, please see IC-NO3-M, 1,000 g/mL Nitrogen in H2O instead.
Waters Corp IEX Cation Test Standard 186006870
A specialized mix of 3 Intact proteins; Ribonuclease A , Cytochrome C,and Chicken Lysozyme that is formulated to benchmark and test Cation Exchange Columns. This standard is a lyophilized powder packaged in a Waters Truview Max Recovery Vial. It is recommended that this standard be used on a regular basis for benchmarking column and system performance, similar to the QCRM product line.
Thermo Scientific Dionex Nitrite Standard (1000mg/L), 125mL
For Use With Routine anion determinations | Type: Standard | Standard Components Nitrite 1000mg/L | Volume 125 mL
Apexbio Technology LLC AOA hemihydrochloride 2921-14-4 1g
Aminooxyacetic acid hemihydrochloride (AOA hemihydrochloride CAS 2921-14-4) is a biochemical modulator that inhibits the malate-aspartate shuttle thereby disrupting the transfer of NADH between mitochondria and the cytosol Additionally AOA suppresses -aminobutyric acid transaminase (GABA-T) leading to reduced degradation of -aminobutyric acid (GABA) This compound is widely utilized in studies of cellular energy metabolism bioenergetic processes and mechanistic investigations of GABA-related metabolic pathways in the nervous system
Apexbio Technology LLC Raceanisodamine 17659-49-3 1g
Raceanisodamine (CAS 17659-49-3) is a naturally occurring tropane alkaloid primarily derived from the roots of Anisodus tanguticus It functions as a weak antagonist of 1-adrenergic receptors which are critical in regulating smooth muscle contraction cardiovascular activity and neurological processes In receptor-binding studies raceanisodamine inhibited the interaction of WB-4101 and clonidine with brain membrane preparations with reported pKi values of 2 63 and 1 61 respectively Additionally raceanisodamine exhibits antioxidant properties and offers cellular protection against free radical-induced damage These characteristics support its use in research focused on receptor pharmacology oxidative stress and neuroprotective mechanisms
